If you are starting the task of organizing, take baby steps. The process can be long and exhausting. One section at a time. When is the best time of day? That’s up to you. I like mornings when I am fresh, alert and the Nevada heat is still at its lowest.
Night owl? Work on a drawer with a nice glass of wine and music while you sort. Maybe the kids are tucked in and you can enjoy a couple hours with no interruptions.
Some have energy after a work-out and may be grubby already, so tackle a couple things in the garage before your shower.
In any event set a timer and allow yourself only that amount of time. Start with an hour and build up to a few at a time. Never let the task take over the entire weekend. Stop for water, snacks or a meal… maybe order a pizza delivery as a treat and reward.
Wrap it up when the timer goes off and feel good about your accomplishment.